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Showing 1–4 of 4 results
Advanced filters: Author: "Jorge Oksenberg" Clear advanced filters
  • Progress in understanding the genetic basis of susceptibility to multiple sclerosis — a debilitating and genetically complex disease — is being obtained by a combination of advances in genome studies (through genome-wide association studies) and powerful systems-level approaches.

    • Jorge R. Oksenberg
    • Sergio E. Baranzini
    • Stephen L. Hauser
    Reviews
    Nature Reviews Genetics
    Volume: 9, P: 516-526
  • In this Review, Oksenberg and Baranzini examine the field of multiple sclerosis (MS) genetics, focusing on the abundance of data that has been generated from genome-wide association studies. The authors also highlight the challenges that lie ahead in this field, including the need for functional studies to connect the genetic variation observed in patients with the underlying pathophysiology of this condition.

    • Jorge R. Oksenberg
    • Sergio E. Baranzini
    Reviews
    Nature Reviews Neurology
    Volume: 6, P: 429-437