Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed particles involved in a multitude of biological processes, including the development and homeostasis of cartilage tissue. In this Perspectives article, the authors describe the current knowledge of the functions of EVs in joint physiology and explore the therapeutic potential of EVs as tools to deliver biologically-active therapeutic agents to joints.
- Jos Malda
- Janneke Boere
- Marca H. M. Wauben