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Showing 1–2 of 2 results
Advanced filters: Author: "Jos W M van der Meer" Clear advanced filters

  • This Review describes the host immune response toCandida fungal infections. The authors detail the innate and adaptive immune mechanisms, as well as the non-immune mechanisms, that are involved in the antifungal response. They also discuss emerging evidence suggesting that both innate and adaptive immune cells contribute to immune memory against Candidaspecies.

    • Mihai G. Netea
    • Leo A. B. Joosten
    • Frank L. van de Veerdonk
    Reviews
    Nature Reviews Immunology
    Volume: 15, P: 630-642

  • Blockade of the pro-inflammatory cytokine interleukin-1 (IL-1) is emerging as an effective approach for the treatment of an increasing number of diseases. Here, Dinarello and colleagues discuss the pathogenic roles of IL-1, present therapeutic strategies aimed at modulating the activity of this cytokine and review clinical trial data for multiple indications.

    • Charles A. Dinarello
    • Anna Simon
    • Jos W. M. van der Meer
    Reviews
    Nature Reviews Drug Discovery
    Volume: 11, P: 633-652