Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: "Joshua D. Rabinowitz" Clear advanced filters

  • The molecule succinate, which is a product of metabolism, promotes heat production and therefore calorie burning in brown fat in mice. This discovery could have implications for combating obesity in humans.

    • Sheng Hui
    • Joshua D. Rabinowitz
    News & Views
    Nature
    Volume: 560, P: 38-39

  • The phenomenon of catabolite repression enables microorganisms to use their favourite carbon source first. New work reveals α-ketoacids as key effectors of this process, with their levels regulating gene expression. See Article p.301

    • Joshua D. Rabinowitz
    • Thomas J. Silhavy
    News & Views
    Nature
    Volume: 500, P: 283-284

  • Metabolic aberrations affecting protein and DNA methylation are a potential source of cancer. A new study shows that the metabolic enzyme nicotinamide N-methyl-transferase, which is overexpressed in several types of tumors, can enhance cancer aggressiveness by draining methyl groups from S-adenosyl-methionine.

    • Tomer Shlomi
    • Joshua D Rabinowitz
    News & Views
    Nature Chemical Biology
    Volume: 9, P: 293-294

  • Learning metabolism inevitably involves memorizing pathways. The teacher's challenge is to motivate memorization and to help students progress beyond it. To this end, students should be taught a few fundamental chemical reaction mechanisms and how these are repeatedly used to achieve pathway goals. Pathway knowledge should then be reinforced through quantitative problems that emphasize the relevance of metabolism to bioengineering and medicine.

    • Joshua D Rabinowitz
    • Livia Vastag
    Comments & Opinion
    Nature Chemical Biology
    Volume: 8, P: 497-501