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Showing 1–5 of 5 results
Advanced filters: Author: "Juthathip Mongkolsapaya" Clear advanced filters

  • Due to the focus of vaccination on the SARS CoV-2 spike protein, spike has been associated with high levels of viral mutation and subsequent immune escape. Here the authors study a conserved epitope in SARS CoV-2 sub-domain-1 and characterise the neutralising antibody response and evasion in contemporary SARS COV-2 viral strains.

    • Daming Zhou
    • Piyada Supasa
    • Gavin R. Screaton
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • Immunity to one serotype of dengue virus can worsen disease following exposure to another serotype, a process called ‘antibody-dependent enhancement’. Grimes and colleagues characterize the function and structural basis of an unusual, potent and broadly neutralizing antibody that lacks such activity.

    • Max Renner
    • Aleksandra Flanagan
    • Jonathan M. Grimes
    Research
    Nature Immunology
    Volume: 19, P: 1248-1256

  • This Review describes the role of the immune system in dengue pathogenesis. The authors also discuss new insights gained from human monoclonal antibodies against dengue virus as well as the recent vaccine trials and the challenges to develop an effective dengue vaccine.

    • Gavin Screaton
    • Juthathip Mongkolsapaya
    • Catherine Roberts
    Reviews
    Nature Reviews Immunology
    Volume: 15, P: 745-759