Findings from laboratory studies have indicated that long-chain omega-3 fatty acids, which are found in abundance in fish, have neuroprotective properties against cognitive decline and dementia. As Majid et al. report in this article, however, the clinical trials conducted to date have failed to support a role for omega-3 fatty acids in the treatment of Alzheimer disease or other dementias. Ongoing clinical trials are expected to provide more-definitive answers in the next 2–3 years.
- Majid Fotuhi
- Payam Mohassel
- Kristine Yaffe
