The detection of antiphospholipid antibodies is important to confirm the occurrence of antiphospholipid syndrome, but current assays fail to convincingly correlate the presence of these antibodies with the incidence of thrombosis, a characteristic of the disease. De Laat and colleagues outline newly developed assays to detect antiphospholipid antibodies, the correlation of these assays with clinical symptoms, and potential pathogenic mechanisms to explain the occurrence of these symptoms.
- Bas de Laat
- Koen Mertens
- Philip G de Groot
