The immunomodulatory properties of vitamin D suggest it plays a central part in inflammatory diseases such as rheumatoid arthritis, a link that has been reinforced by findings from epidemiological andin vitro studies. In this Review, Jeffery et al. provide an overview of the known effects of vitamin D in the immune system and discuss how manipulation of the vitamin D pathway might be used for therapeutic purposes.
- Louisa E. Jeffery
- Karim Raza
- Martin Hewison
