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Showing 1–5 of 5 results
Advanced filters: Author: "Kenneth R Chien" Clear advanced filters
  • MicroRNAs are natural, single-stranded, small RNA molecules thought to control gene expression. Four studies indicate that specific microRNA sequences can regulate heart function in development and disease.

    • Kenneth R. Chien
    News & Views
    Nature
    Volume: 447, P: 389-390
  • The key challenge in the field of molecular and cell-based therapies for heart regeneration is controlled delivery.

    • Boon-Seng Soh
    • Hao Wu
    • Kenneth R Chien
    News & Views
    Nature Biotechnology
    Volume: 31, P: 209-211
  • An area of injured heart in zebrafish embryos repairs itself using cells from neighbouring areas. The regenerating cells seem to originate from an intermediate progenitor-cell population. See Letter p.497

    • Kenneth R. Chien
    News & Views
    Nature
    Volume: 498, P: 439-440
  • The adult human heart lacks sufficient regenerative capacity to recover after a myocardial infarction. Cell-based therapy has emerged as a potential treatment for the failing heart; however, a key issue for the success of future cell-based therapies is the ability to obtain patient-specific high-quality cardiomyocytes in a fast and efficient manner. Recent progress has been made towards this goal using reprogramming-based approaches.

    • Huansheng Xu
    • B. Alexander Yi
    • Kenneth R. Chien
    News & Views
    Nature Cell Biology
    Volume: 13, P: 191-193