The field of Barrett esophagus is evolving. New definitions of the disorder have had an immediate impact on cancer risk and screening. New hypotheses elucidating progression to intestinal metaplasia have been proposed. Advances in imaging techniques have facilitated the diagnosis of Barrett esophagus and ablative techniques are becoming increasingly accepted treatments. This Review provides a timely update on the advances in understanding of the pathogenesis, diagnosis and treatment of this disorder.
- Rami J. Badreddine
- Kenneth K. Wang
