Heat shock proteins (HSPs) are involved in regulation of androgen receptor function, making them targets for therapeutic modulation in the treatment of castration-resistant prostate cancer (CRPC). In this Review, Azad and colleagues discuss HSPs, their roles in CRPC, and the state of current clinical research into HSP blockade.
- Arun A. Azad
- Amina Zoubeidi
- Kim N. Chi
