Atg32 is required for mitophagy in yeast, however, a mammalian homologue of this protein has not been identified. Murakawaet al. identify Bcl-2-like protein 13 as a functional homologue of Atg32 in mammalian cells, and show that this protein can rescue mitophagy in Atg32-deficient yeast cells.
- Tomokazu Murakawa
- Osamu Yamaguchi
- Kinya Otsu