Bacterial ADP-ribosyltransferase toxins (bARTTs) transfer ADP-ribose to a range of eukaryotic proteins to promote bacterial pathogenesis. In this Review, the authors discuss the structural and functional properties of the most recently identified novel bARTTs, which are produced by various human, insect and plant pathogens and were identified using bioinformatic analyses.
- Nathan C. Simon
- Klaus Aktories
- Joseph T. Barbieri