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Showing 1–7 of 7 results
Advanced filters: Author: "Konrad Hochedlinger" Clear advanced filters
  • Four leading researchers contribute their personal opinions on recent progress and current challenges in induced pluripotent stem cell research. Their varied perspectives suggest that for clinical applications there is cause for optimism, tempered with caution, and they highlight exciting recent advances in reprogramming and differentiation.

    • Juan Carlos Izpisúa Belmonte
    • James Ellis
    • Shinya Yamanaka
    Reviews
    Nature Reviews Genetics
    Volume: 10, P: 878-883
  • Six scientists in the field of stem cell research comment on our basic understanding of stem cells and other pluripotent cells, on their potential therapeutic use and on key challenges that remain.

    • Cédric Blanpain
    • George Q. Daley
    • Shinya Yamanaka
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 13, P: 471-476
  • A transposon-based approach has been added to the growing arsenal of technologies to produce transgene-free and potentially safer induced pluripotent stem cells.

    • Matthias Stadtfeld
    • Konrad Hochedlinger
    News & Views
    Nature Methods
    Volume: 6, P: 329-330
  • Induced pluripotent stem cells offer promise for patient-specific regenerative therapy. But a study now cautions that, even when immunologically matched, these cells can be rejected after transplantation. See Letter p.212

    • Effie Apostolou
    • Konrad Hochedlinger
    News & Views
    Nature
    Volume: 474, P: 165-166
  • Researchers have coaxed cultured embryonic stem cells to develop into eggs that then give rise to normal offspring. The discovery should help to decode the molecular basis of gamete formation and might lead to treatments for infertility.

    • Sihem Cheloufi
    • Konrad Hochedlinger
    News & Views
    Nature
    Volume: 491, P: 535-536
  • The mechanisms that underlie enforced transitions between mature cell lineages are poorly understood. Profiling single skin cells that are induced to become neurons reveals that, unexpectedly, they often become muscle. See Letter p.391

    • Bruno Di Stefano
    • Konrad Hochedlinger
    News & Views
    Nature
    Volume: 534, P: 332-333