Nys et al. discuss the emerging role of autophagy as a regula-tor of immune and/or inflammatory responses and as a stress adaptive mechanism, and analyze its value as a diagnostic and/or therapeutic target in Crohn's disease. Moreover, they highlight how several drugs used in the treatment of Crohn's disease have already been shown to affect autophagy induction as part of their mode of action.
- Kris Nys
- Patrizia Agostinis
- Séverine Vermeire