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Showing 1–4 of 4 results
Advanced filters: Author: "Lewis C. Cantley" Clear advanced filters
  • The vast majority of the research into cancer metabolism has been limited to a handful of metabolic pathways, with other pathways being sidelined. This Progress article brings to light the potential contribution of fatty acid oxidation to cancer cell function.

    • Arkaitz Carracedo
    • Lewis C. Cantley
    • Pier Paolo Pandolfi
    Reviews
    Nature Reviews Cancer
    Volume: 13, P: 227-232
  • Fructose and glucose have the same caloric value, but the two sugars are metabolized differently. It emerges that mice that cannot metabolize fructose are healthier when placed on carbohydrate-rich diets.

    • Costas A. Lyssiotis
    • Lewis C. Cantley
    News & Views
    Nature
    Volume: 502, P: 181-182
  • Seemingly unrelated mutations that drive cancer share the ability to promote nutrient uptake and metabolism conducive to cell growth.

    • Jason W Locasale
    • Lewis C Cantley
    • Matthew G Vander Heiden
    News & Views
    Nature Biotechnology
    Volume: 27, P: 916-917
  • Phosphatidylinositol 3-kinases (PI3Ks) are members of a unique and conserved family of intracellular lipid kinases that regulate a wide range of biological functions. Our understanding of the intricate regulation of this pathway is being applied to identify therapeutic strategies for diabetes and cancer.

    • Jeffrey A. Engelman
    • Ji Luo
    • Lewis C. Cantley
    Reviews
    Nature Reviews Genetics
    Volume: 7, P: 606-619