Most cases of stroke occur in the elderly, and stroke morbidity and mortality rates rise with increasing age. In this Review, Chen and colleagues examine the relationship between age and ischemic stroke, including discussion of the age-related changes that make elderly people particularly vulnerable to stroke and the factors that might be responsible for the poor outcomes observed in this patient group.
- Ruo-Li Chen
- Joyce S. Balami
- Alastair M. Buchan