Song et al. describe the evidence connecting neurotrophins and lower urinary tract function, with particular regard to brain-derived neurotrophic factor, stress urinary incontinence and bladder pain syndrome/interstitial cystitis, and discuss the potential for future therapies based on modulation of neurotrophin levels in the urinary tract and its innervating nerves.
- Qi-Xiang Song
- Christopher J. Chermansky
- Margot S. Damaser
