Diabetes mellitus adversely affects the skeleton and is associated with an increased risk of osteoporosis and fragility fractures. This Review provides an overview of the effects of diabetes mellitus on osteoporosis and fractures, discussing molecular and cellular data, preclinical models and human studies in the context of the epidemiology, pathogenesis and clinical implications of impaired bone health.
- Christine Hamann
- Stephan Kirschner
- Lorenz C. Hofbauer
