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Advanced filters: Author: "Louis P Dehner" Clear advanced filters

  • Germline mutations inDICER1 can lead to DICER1 syndrome, which is characterized by the predisposition of various types of cancer in childhood and during early adulthood. Additionally, specific DICER1 mutations occur in tumours. This Review discusses germline and somatically-acquired DICER1mutations and their effects on tumorigenesis.

    • William D. Foulkes
    • John R. Priest
    • Thomas F. Duchaine
    Reviews
    Nature Reviews Cancer
    Volume: 14, P: 662-672