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Showing 1–6 of 6 results
Advanced filters: Author: "Ludovic Orlando" Clear advanced filters

  • An extensive genomic time series has been produced for 356 humans from across ice-age Europe. The data reveal how climate change affected the ranges of hunter-gatherer populations as they developed diverse cultures.

    • Ludovic Orlando
    News & Views
    Nature
    Volume: 615, P: 41-42

  • Sequencing genomes of ancient specimens, including human ancestors, can provide rich insights into evolutionary histories. However, ancient DNA samples are frequently degraded, damaged and contaminated with ancient and modern DNA from various sources. This Review describes the methodological and bioinformatic advances that allow these challenges to be overcome in order to process and sequence ancient samples for genome reconstruction, as well as recent progress in characterizing ancient epigenomes.

    • Ludovic Orlando
    • M. Thomas P. Gilbert
    • Eske Willerslev
    Reviews
    Nature Reviews Genetics
    Volume: 16, P: 395-408

  • This Primer outlines the best ways to find, handle and analyse ancient DNA from various sources. The authors summarize ethical considerations and the importance of working closely with all stakeholders, including archaeologists, curators and descendant communities.

    • Ludovic Orlando
    • Robin Allaby
    • Christina Warinner
    Reviews
    Nature Reviews Methods Primers
    Volume: 1, P: 1-26

  • Improvements in DNA extraction methods and sequencing technologies have led to the successful sequencing of numerous whole ancient genomes. In this Review, the authors provide an overview of how ancient DNA has informed our understanding of the domestication of various animal species, including dogs, pigs, cattle, goats and chickens.

    • Laurent A. F. Frantz
    • Daniel G. Bradley
    • Ludovic Orlando
    Reviews
    Nature Reviews Genetics
    Volume: 21, P: 449-460