Pain is a debilitating symptom of juvenile idiopathic arthritis (JIA) that can persist despite effective disease control. Insights into the underlying mechanisms of pain in JIA could highlight new treatment approaches and improve management. Here, the neurobiological basis of pain in JIA is described, using findings from animal models to inform the situation in humans.
- Luke La Hausse de Lalouvière
- Yiannis Ioannou
- Maria Fitzgerald