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Showing 1–3 of 3 results
Advanced filters: Author: "M Juliana McElrath" Clear advanced filters

  • The extraordinary diversity of HIV is a major barrier in the path of developing a vaccine. One way forward may be mosaic antigens—biometrically designed genes that maximize overlap between sequences used in the vaccine and circulating HIV-1 strains worldwide (pages 319–323 and 324–328).

    • Lawrence Corey
    • M Juliana McElrath
    News & Views
    Nature Medicine
    Volume: 16, P: 268-270

  • The expression of antibodies to protect against an infectious disease can be achieved by the injection into the host of vectors carrying the gene to the relevant antibodies. Here the authors demonstrate the applicability of this technique to protection from HIV in a humanized mouse model, showing this to be a valid route to pursue in vaccine development for humans (pages 296–300).

    • Lawrence Corey
    • M Juliana McElrath
    News & Views
    Nature Medicine
    Volume: 20, P: 241-242

  • Infection by HIV requires the virus to breach the mucosal barrier to gain access to the immune cells that it infects. But what are the immediate events that follow HIV exposure at genital mucosal sites and what are the key cells that facilitate HIV invasion?

    • Florian Hladik
    • M. Juliana McElrath
    Reviews
    Nature Reviews Immunology
    Volume: 8, P: 447-457