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  • In this Review, Tentler et al. present the opportunities and challenges of using patient-derived tumour xenograft models in oncology drug development, provide specific disease examples, and describe concepts regarding predictive biomarker development and future applications.

    • John J. Tentler
    • Aik Choon Tan
    • S. Gail Eckhardt
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 9, P: 338-350