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Showing 1–4 of 4 results
Advanced filters: Author: "M Schmidt" Clear advanced filters

  • Plasmonic nanoparticles are useful as optical sensors, but their spectral resolution is hindered by the linewidth of the plasmon resonance. Schmidtet al. find that coupling this resonance to a microcavity creates hybrid modes with enhanced sensing figure-of-merit and improved frequency resolution.

    • Markus A. Schmidt
    • Dang Yuan Lei
    • Stefan A. Maier
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-8

  • In this Analysis article, Morris and Schmidt report the results of surveys searching for high-affinity terminal oxidase genes in sequenced bacterial genomes and shotgun metagenomes. They find that bacteria with the potential to respire under microoxic conditions are phylogenetically diverse and intriguingly widespread in nature, and go on to highlight the importance of microaerobic metabolism in host-associated bacteria.

    • Rachel L. Morris
    • Thomas M. Schmidt
    Research
    Nature Reviews Microbiology
    Volume: 11, P: 205-212

  • Mixtures of interacting compounds produced by plants may provide important combination therapies that simultaneously affect multiple pharmacological targets and provide clinical efficacy beyond the reach of single compound–based drugs. Developing innovative scientific methods for discovery, validation, characterization and standardization of these multicomponent botanical therapeutics is essential to their acceptance into mainstream medicine.

    • Barbara M Schmidt
    • David M Ribnicky
    • Ilya Raskin
    Comments & Opinion
    Nature Chemical Biology
    Volume: 3, P: 360-366

  • Evgenovet al. review the discovery, biochemistry and pharmacology of nitric oxide-independent stimulators and activators of soluble guanylate cyclase, a key signal-transduction enzyme, and discuss their potential for treating arterial and pulmonary hypertension, heart failure, atherosclerosis, thrombosis, erectile dysfunction, renal fibrosis and failure, and liver cirrhosis.

    • Oleg V. Evgenov
    • Pál Pacher
    • Johannes-Peter Stasch
    Reviews
    Nature Reviews Drug Discovery
    Volume: 5, P: 755-768