The important functional roles of non-protein-coding RNA have come to light since the discovery of the enzymatic activity of RNA in the mid 1980s. This Review discusses what is currently known about the role of a class of non-protein-coding RNA called microRNAs in the heart. Since the first report on this topic was published in 2005, intense research has been conducted to elucidate how microRNAs are involved in cardiovascular physiology and pathology.
- Michael V. G. Latronico
- Gianluigi Condorelli
