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Showing 1–2 of 2 results
Advanced filters: Author: "Malcolm J. Moore" Clear advanced filters

  • The role of preoperative biliary drainage (PBD) before surgery for tumors of the pancreatic head causing biliary obstruction has been controversial. A recent randomized trial revealed a higher complication rate with PBD in comparison to early surgery (within one week). Based on this trial, early surgery should be considered the preferred approach; however, the role of PBD when early surgery is not possible remains unclear.

    • Daniel J. Renouf
    • Malcolm J. Moore
    News & Views
    Nature Reviews Clinical Oncology
    Volume: 7, P: 246-247

  • Pancreatic adenocarcinoma is the most lethal of the solid tumors and most patients present with locally advanced or metastatic disease that precludes curative resection. Considerable efforts have been made during the past decade to identify better systemic treatments. The authors of this Review discuss the current standards of care for patients with locally advanced and metastatic pancreatic carcinoma, and outline future directions for the development of new treatment strategies.

    • Anastasios Stathis
    • Malcolm J. Moore
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 7, P: 163-172