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Showing 1–11 of 11 results
Advanced filters: Author: "Marc Veldhoen" Clear advanced filters

  • Type-1 regulatory T cells promoted the generation of CD8+ tissue-resident memory T (TRM) cells during intracellular infections in the gut. Here, the authors show that the establishment TRM cells more broadly depends on the presence of regulatory T cells matching the type of infection.

    • Leandro Barros
    • Daryna Piontkivska
    • Cristina Ferreira
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Three new studies demonstrate that development of human TH-17 cells requires transforming growth factor-β and one or more proinflammatory cytokines, which are the same requirements as for mouse TH-17 development.

    • Anne O'Garra
    • Brigitta Stockinger
    • Marc Veldhoen
    News & Views
    Nature Immunology
    Volume: 9, P: 588-590

  • Immunohomeostasis prevents pathology resulting from immune activation. Two new studies link its regulation with the activation of the aryl hydrocarbon receptor, a known mediator of the toxic effects of xenobiotic ligands, in a subset of T lymphocytes.

    • Marc Veldhoen
    News & Views
    Nature Immunology
    Volume: 11, P: 779-781

  • Dietary habits have always been associated with the robustness of the immune system. Here, the molecular links between dietary compounds and immune regulation in the intestine are discussed, with a focus on the central role of nuclear receptors.

    • Marc Veldhoen
    • Verena Brucklacher-Waldert
    Reviews
    Nature Reviews Immunology
    Volume: 12, P: 696-708

  • Here, Veldhoen and Simas discuss why immunity to SARS-CoV-2 in populations may ultimately be driven by the endemic presence of the virus and not rely on continued mass vaccination programmes.

    • Marc Veldhoen
    • J. Pedro Simas
    Comments & Opinion
    Nature Reviews Immunology
    Volume: 21, P: 131-132

  • The receptor for interleukin-7 is a susceptibility factor in multiple sclerosis, but its exact role in the disease has been unclear. New findings outline a function for interleukin-7 in the biology of T helper 17 cells, a subset of T cells recently identified as key players in autoimmune disorders (pages 191–197).

    • Marc Veldhoen
    • Benedict Seddon
    News & Views
    Nature Medicine
    Volume: 16, P: 166-168

  • There are clear epidemiological links between nutrition and immunological function, but a dearth of mechanistic insights has made this topic controversial. Veldhoen and Veiga-Fernandes discuss this controversy and explore ways to take this research forward.

    • Marc Veldhoen
    • Henrique Veiga-Fernandes
    Comments & Opinion
    Nature Immunology
    Volume: 16, P: 215-219

  • Although interleukin 17 (IL-17) has modest activity on its own, it has a substantial impact in immunity through its synergistic action with other factors and its self-sustaining feedback loop. Veldhoen discusses the role of IL-17 during infections.

    • Marc Veldhoen
    Reviews
    Nature Immunology
    Volume: 18, P: 612-621

  • Recent studies have provided insight into how the environment, and in particular the diet, influence the development of lymphocytes. Emerging studies indicate a role for this immune development in inflammatory disease.

    • Marc Veldhoen
    • Cristina Ferreira
    Reviews
    Nature Medicine
    Volume: 21, P: 709-718