The glomerular parietal epithelial cell (PEC)—a resident glomerular cell type—has been under active study in recent years, improving the understanding and definition of how these cells behave normally and in glomerular disease. Here, the authors discuss model systems to study PECs, how PECs might contribute to glomerulosclerosis, crescent and pseudocrescent formation and how PECs handle filtered albumin.
- Stuart J. Shankland
- Bart Smeets
- Marcus J. Moeller
