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Showing 1–3 of 3 results
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  • Four studies detail changes in how DNA is wrapped around histone proteins and in molecular modifications to histones that occur after fertilization. The results shed light on the early regulation of gene expression. See Letters p.548, p.553 & p.558

    • Juan M. Vaquerizas
    • Maria-Elena Torres-Padilla
    News & Views
    Nature
    Volume: 537, P: 494-496

  • Three studies highlight DUX proteins as key transcription factors regulating embryonic genome activation in early mammalian development.

    • Ane Iturbide
    • Maria-Elena Torres-Padilla
    News & Views
    Nature Genetics
    Volume: 49, P: 820-821

  • It is unclear how totipotent embryonic cells acquire their fate and what role chromatin dynamics have in this process. Technological advances in studying single cells have begun to improve our understanding of the mechanisms underlying lineage allocation and cell plasticity in early mammalian development.

    • Adam Burton
    • Maria-Elena Torres-Padilla
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 15, P: 723-735