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Showing 1–8 of 8 results
Advanced filters: Author: "Martin F Pera" Clear advanced filters

  • In the earliest stages of mammalian development, individual cells possess the unrestricted potential to form a new organism. Researchers are closing in on the goal of growing these cells in the laboratory.

    • Martin F. Pera
    News & Views
    Nature
    Volume: 617, P: 683-684

  • A comparison of embryonic stem cells and induced pluripotent stem cells on the proteome level reveals subtle distinctions between these cell types that might explain differences in their ability to differentiate into specific lineages.

    • Martin F Pera
    News & Views
    Nature Methods
    Volume: 8, P: 807-808

  • Manipulating cells from adult human tissue, scientists have generated cells with the same developmental potential as embryonic stem cells. The research opportunities these exciting observations offer are limitless.

    • Martin F. Pera
    News & Views
    Nature
    Volume: 451, P: 135-136

  • Retroviral marking of single human embryonic stem cells shows that cultures of these cells contain subpopulations with distinct functional properties.

    • Martin F Pera
    News & Views
    Nature Methods
    Volume: 7, P: 885-887

  • The simple addition of vitamin C to cell culture medium can induce extensive remodeling of the cellular epigenome and facilitates reprogramming of somatic cells to pluripotency. A new study shows that the activity of the enzyme TET1 can inhibit or enhance reprogramming efficiency, dependent on the presence or absence of vitamin C.

    • Martin F Pera
    News & Views
    Nature Genetics
    Volume: 45, P: 1412-1413

  • Induced pluripotent stem cells have great therapeutic potential. But genomic and epigenomic analyses of these cells generated using current technology reveal abnormalities that may affect their safe use. See Articles p.58, p.63 & p.68

    • Martin F. Pera
    News & Views
    Nature
    Volume: 471, P: 46-47

  • New techniques circumvent a roadblock to the production of embryonicstem-cell-like lines from adult tissue. Such reprogrammed cell lines should be much safer to use for therapy.

    • Martin F. Pera
    News & Views
    Nature
    Volume: 458, P: 715-716

  • Induced pluripotent stem cells have been generated from mouse and human adult fibroblasts without the tumor-causing gene c-Myc.

    • Martin F Pera
    • Kouichi Hasegawa
    News & Views
    Nature Biotechnology
    Volume: 26, P: 59-60