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Advanced filters: Author: "Martin H de Borst" Clear advanced filters

  • Dysregulated phosphate metabolism is a common consequence of kidney disease and renal transplantation. In this Review, Martin H. de Borst and colleagues outline the pathophysiology of dysregulated phosphate metabolism in renal transplant recipients and discuss the effect of this dysregulation on the cardiovascular system, bone, and the kidney graft. They also propose possible strategies to correct phosphate abnormalities in these patients.

    • Leandro C. Baia
    • Ita Pfeferman Heilberg
    • Martin H. de Borst
    Reviews
    Nature Reviews Nephrology
    Volume: 11, P: 656-666

  • Identification of the molecular pathways involved in renal pathophysiology can yield targets for intervention and aid tailored therapy. de Borst and colleagues provide an introduction to the tools that can be used to pinpoint genes involved in renal disease, including gene expression arrays, linkage analysis, association studies and animal models. Examples of genes that have been identified using these techniques are highlighted.

    • Martin H de Borst
    • Ariela Benigni
    • Giuseppe Remuzzi
    Reviews
    Nature Clinical Practice Nephrology
    Volume: 4, P: 265-276