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Showing 1–8 of 8 results
Advanced filters: Author: "Martin J. Blaser" Clear advanced filters
  • The increase in allergic diseases that has occurred in developing countries in recent years has been attributed to a decrease in exposure to the microorganisms in the environment. Blaser and Falkow reflect that this increase, as well as the ongoing obesity epidemic and increased susceptibility to infectious disease, might instead be the result of changes in the human microbiota.

    • Martin J. Blaser
    • Stanley Falkow
    Comments & Opinion
    Nature Reviews Microbiology
    Volume: 7, P: 887-894
  • The function ofHelicobacter pyloriin inflammation-induced gastric cancers is one of the best studied infectious etiologies. A better understanding of the molecular mechanisms underpinning this process, and the role of inflammation in malignancies seen in other organs where inflammation is common, will lead to novel cancer prevention and treatment strategies for gastric cancers and other malignancies.

    • Steven F Moss
    • Martin J Blaser
    Reviews
    Nature Clinical Practice Oncology
    Volume: 2, P: 90-97
  • A growing understanding of the relationship between the microbiome and human health is made possible by advances in sequencing technologies and computational tools. These studies highlight how the composition and function of the microbiome varies across individuals and anatomical sites, over time, and also in disease.

    • Ilseung Cho
    • Martin J. Blaser
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 260-270
  • The article focuses on the tensions between the opposing forces of maintaining genome integrity and increasing genome diversification inHelicobacter pylori. The authors propose that this generates a dynamic pool of genetic variants that is sufficiently diverse to occupy the different niches in the stomach.

    • Josephine Kang
    • Martin J. Blaser
    Reviews
    Nature Reviews Microbiology
    Volume: 4, P: 826-836
  • Colonization of an infant with their microbiota in early life is important for normal development of host metabolism. In this Perspectives article, Cox and Blaser posit that exposure to antibiotics that disrupt either vertical transmission or colonization and maturation of the microbiota in the infant can lead to adverse consequences such as obesity in adulthood.

    • Laura M. Cox
    • Martin J. Blaser
    Reviews
    Nature Reviews Endocrinology
    Volume: 11, P: 182-190
  • Here, Blaser, Bork, Fraser, Knight and Wang highlight the most exciting findings in the field of microbiome research and discuss what will be necessary to obtain a better understanding of the role of the microbiota in human health and disease, and to develop microbiota-based therapies.

    • Martin Blaser
    • Peer Bork
    • Jun Wang
    Reviews
    Nature Reviews Microbiology
    Volume: 11, P: 213-217