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Showing 1–5 of 5 results
Advanced filters: Author: "Matt Kaeberlein" Clear advanced filters
  • Two animal studies show that restricting the dietary intake of branched-chain amino acids can extend lifespan by modulating the mTOR signalling pathway. But more research is needed before this diet should be recommended in people.

    • Cristal M. Hill
    • Matt Kaeberlein
    News & Views
    Nature
    Volume: 589, P: 357-358
  • Understanding how a low calorie intake slows ageing could revolutionize the way that we treat age-related diseases. One potential key to such treatments could be to enhance the local environment of stem cells. See Article p.490

    • Fresnida J. Ramos
    • Matt Kaeberlein
    News & Views
    Nature
    Volume: 486, P: 477-478
  • A mother's instinct is to protect her children at any cost. In the budding yeast Saccharomyces cerevisiae this 'maternal instinct' comes at a high price — accelerated ageing and premature death.

    • Matt Kaeberlein
    News & Views
    Nature
    Volume: 454, P: 709-710
  • The small molecule rapamycin, already approved for clinical use for various human disorders, has been found to significantly increase lifespan in mice. Is this a step towards an anti-ageing drug for people?

    • Matt Kaeberlein
    • Brian K. Kennedy
    News & Views
    Nature
    Volume: 460, P: 331-332
  • Identifying therapies to slow down ageing and delay age-associated diseases is a primary goal of ageing-related research. Resveratrol and rapamycin were first found to promote longevity in yeast, and their effects were then extended to several organisms. Spermidine is a new longevity drug that can increase life span in yeast, nematodes and flies, possibly through an effect on chromatin-mediated regulation of gene expression.

    • Matt Kaeberlein
    News & Views
    Nature Cell Biology
    Volume: 11, P: 1277-1278