Recent years have seen several important advances in the tools available to interrogate the function of specific genes. Here, Heidenreich and Zhang describe the advantages of the precise and efficient CRISPR–Cas9 (clustered regularly interspaced short palindromic repeat–CRISPR-associated protein) system for gene editing and outline how this approach may benefit research into nervous system function and disease.
- Matthias Heidenreich
- Feng Zhang
