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Showing 1–4 of 4 results
Advanced filters: Author: "Matthias Heinig" Clear advanced filters

  • Numerous disease-associated variants have been described in GWAS for atrial fibrillation. Here the authors integrate omics data to investigate the consequences of genetic variants for transcript and protein levels in the atrium of the human heart. With this multi-omics approach, authors reveal the regulatory network underlying atrial fibrillation and provide a resource for cardiac gene prioritization.

    • Ines Assum
    • Julia Krause
    • Matthias Heinig
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • scRNASeq data is revolutionizing our understanding of biological systems, but is still expensive to generate. Here, the authors present a statistical framework that facilitates informed multi-sample experimental design to reduce unnecessary costs and maximize the utility of the generated data.

    • Katharina T. Schmid
    • Barbara Höllbacher
    • Matthias Heinig
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18