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Showing 1–2 of 2 results
Advanced filters: Author: "Mete Civelek" Clear advanced filters

  • Genetic and gene expression studies have suggested an important role for KLF14 in metabolic disease. A new study now identifies a network of genes whose expression is associated with KLF14 variation in trans, providing a framework for understanding how KLF14 influences disease risk.

    • Mete Civelek
    • Aldons J Lusis
    News & Views
    Nature Genetics
    Volume: 43, P: 506-508

  • Complex organismal traits, including diseases, are controlled by intricate interactions between multiple genes, intermediate molecular and cellular phenotypes, and environmental influences. This Review describes how systems genetics integrates these layers of information to provide a cohesive understanding of the molecular underpinnings of complex traits.

    • Mete Civelek
    • Aldons J. Lusis
    Reviews
    Nature Reviews Genetics
    Volume: 15, P: 34-48