Dominant mesial temporal lobe resection for pharmacoresistant epilepsy is frequently associated with verbal memory impairment. More-extensive lesioning improves seizure outcome, but further compromises memory. A better understanding of ipsilateral neural structures and networks for verbal memory could improve selectivity of surgical ablation, thereby holding promise for seizure-freedom without memory impairment.
- Michael Duchowny
- Sanjiv Bhatia
