The protein PHF20 is expressed in various cancers, but little is known about its cellular function. Here, Zhang and colleagues show that PHF20 regulates NF-κB signalling by inhibiting the interaction between its subunit p65 and the phosphatase PP2A, thereby maintaining NF-κB in an active state in the nucleus.
- Tiejun Zhang
- Kyeong Ah Park
- Gang Min Hur
