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Advanced filters: Author: "Nancy A. Jenkins" Clear advanced filters

  • Transposon-based insertional mutagenesis (TIM) provides an alternative method for cancer gene discovery. This Review discusses how the mobilization of the transposon Tc1/mariner, Sleeping Beauty (SB), in mouse cells at frequencies high enough to induce cancer has facilitated the identification of the genes and signalling pathways that drive tumour formation.

    • Neal G. Copeland
    • Nancy A. Jenkins
    Reviews
    Nature Reviews Cancer
    Volume: 10, P: 696-706