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Showing 1–4 of 4 results
Advanced filters: Author: "Nicholas J Loman" Clear advanced filters

  • In this Progress article, Pallen, Loman and colleagues present a snapshot of the high-throughput sequencing platforms available to microbiologists today, together with the relevant analytical tools, and evaluate their strengths and weaknesses in obtaining bacterial genome sequences.

    • Nicholas J. Loman
    • Chrystala Constantinidou
    • Mark J. Pallen
    Reviews
    Nature Reviews Microbiology
    Volume: 10, P: 599-606

  • Nanopore sequencing gets a boost with accurate error modeling and variant-calling tools for Oxford Nanopore Technology's highly anticipated MinION platform.

    • Nicholas J Loman
    • Mick Watson
    News & Views
    Nature Methods
    Volume: 12, P: 303-304

  • The first bacterial genome sequence was published 20 years ago. In this Timeline, Loman and Pallen review the first two decades of bacterial genome sequencing, discussing how advances in sequencing technologies and bioinformatics have furthered our understanding of the biology, diversity and evolution of bacteria.

    • Nicholas J. Loman
    • Mark J. Pallen
    Reviews
    Nature Reviews Microbiology
    Volume: 13, P: 787-794

  • Next-generation sequencing has the potential to support public health surveillance systems to improve the early detection of emerging infectious diseases. This Review delineates the role of genomics in rapid outbreak response and the challenges that need to be tackled for genomics-informed pathogen surveillance to become a global reality.

    • Jennifer L. Gardy
    • Nicholas J. Loman
    Reviews
    Nature Reviews Genetics
    Volume: 19, P: 9-20