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Showing 1–3 of 3 results
Advanced filters: Author: "Niklas Mejhert" Clear advanced filters
  • Single-cell studies of human white adipose tissue (WAT) provide insights into the specialized cell types in the tissue. Here the authors combine publicly available and newly generated high-resolution and bulk transcriptomic results from multiple human datasets to provide a comprehensive cellular map of white adipose tissue.

    • Lucas Massier
    • Jutta Jalkanen
    • Niklas Mejhert
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19
  • Maqdasy, Lecoutre et al. show that increased an phosphocreatine/creatine ratio in white adipocytes drives changes in AMP-activated protein kinase activity and promotes white adipocyte inflammation during obesity.

    • Salwan Maqdasy
    • Simon Lecoutre
    • Mikael Rydén
    ResearchOpen Access
    Nature Metabolism
    Volume: 4, P: 190-202
  • Nelson and colleagues compare whole body, skeletal muscle and white adipose tissue insulin resistance in inbred mouse strains fed a chow or a Western diet. They report large strain-related differences in diet-induced effects on weight gain and insulin action, and demonstrate that tissue-specific insulin sensitivity can be disentangled from systemic insulin resistance.

    • Niklas Mejhert
    • Mikael Rydén
    News & Views
    Nature Reviews Endocrinology
    Volume: 18, P: 269-270