Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: "Ola Larsson" Clear advanced filters

  • Metabolic reprogramming is a hallmark of pancreatic ductal adenocarcinoma (PDA). Here, the authors show that in PDA cells redox and central carbon metabolism are driven by an eIF4F dependent translation program, and combined targeting of eIF4A and glutaminase can impact PDA proliferation.

    • Karina Chan
    • Francis Robert
    • Iok In Christine Chio
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16

  • Ternary complex (TC) and eIF4F complex assembly are rate-limiting steps in translation initiation that are regulated by eIF2α phosphorylation and the mTOR/4E-BP pathway. Here the authors show that the protein kinases mTORC1 and CK2 coordinate TC and eIF4F complex assembly through eIF2β to stimulate cell proliferation.

    • Valentina Gandin
    • Laia Masvidal
    • Ivan Topisirovic
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-15

  • Translation of mRNA is controlled by a whole host of tightly regulated processes. In this Focus Review, Piccirillo et al. describe how translational skewing can serve a key role in the immune system.

    • Ciriaco A Piccirillo
    • Eva Bjur
    • Ola Larsson
    Reviews
    Nature Immunology
    Volume: 15, P: 503-511