The heart and kidney can mutually influence each other's function so that dysfunction in one organ can result in dysfunction in the other. In this Review, Khaled Shamseddin and Patrick Parfrey describe the mechanisms involved in this two-way interaction, with reference to the classification of the so-called cardiorenal syndromes introduced in 2008 by Claudio Ronco and colleagues.
- M. Khaled Shamseddin
- Patrick S. Parfrey