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Showing 1–3 of 3 results
Advanced filters: Author: "Paul J. Utz" Clear advanced filters

  • Multiplexed assay technologies at the gene, protein, and cellular levels have enabled the identification of 'actionable biomarkers' that can inform clinical practice. Powerful new methods, including mass cytometry and protein arrays, are reviewed.

    • Holden T. Maecker
    • Tamsin M. Lindstrom
    • C. Garrison Fathman
    Reviews
    Nature Reviews Rheumatology
    Volume: 8, P: 317-328

  • A new single cell detection technology allows simultaneous measurement of up to 100 surface markers and signaling proteins of immune cells. This method provides the opportunity to make great advances into the scientific understanding of rheumatic disease and the provision of individualized patient care.

    • Regina K. Cheung
    • Paul J. Utz
    News & Views
    Nature Reviews Rheumatology
    Volume: 7, P: 502-503

  • Multiplex antigen microarrays can profile the high titers of autoantibodies found in the biological fluids of patients with many autoimmune diseases, which enables rapid identification of antibody and antigen biomarker sets. The potential applications of this technology for improved diagnosis, prognosis and selection of targeted therapies are reviewed in this article.

    • Veronika Sharp
    • Paul J Utz
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 3, P: 96-103