Eicosanoids are major regulators of inflammation and are thought to be involved in the pathogenesis of rheumatic diseases. Here, the authors provide an overview of eicosanoid pathways in a variety of rheumatic diseases (including rheumatoid arthritis, osteoarthritis and gout, among others) and describe how targeting this pathway might lead to novel anti-inflammatory treatment strategies.
- Marina Korotkova
- Per-Johan Jakobsson