In this Review, the authors discuss the clinical features of patients with sporadic pituitary adenomas that are associated withAIP or MEN1mutations, and discuss the molecular mechanisms potentially involved in pituitary adenoma tumorigenesis. They also discuss genetic screening of patients with sporadic pituitary adenomas and investigations of relatives of these patients who also have the same genetic mutations.
- Anne-Lise Lecoq
- Peter Kamenický
- Philippe Chanson
