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Showing 1–2 of 2 results
Advanced filters: Author: "Peter Kraft" Clear advanced filters

  • The success of genome wide association (GWA) studies raises the hope that disease-associated markers will be useful in predicting disease risk. However, the metrics used to report effect sizes in GWA studies are not useful for determining the accuracy of genetic profiles.

    • Peter Kraft
    • Sholom Wacholder
    • Stephen Chanock
    Reviews
    Nature Reviews Genetics
    Volume: 10, P: 264-269

  • A genome-wide association study conducted among women with deleterious BRCA1 mutations has identified a common allele associated with breast cancer risk in BRCA1 carriers and estrogen receptor–negative breast cancer in the general population. This suggests that genetic association studies focused on particular subtypes may provide further insight into complex diseases.

    • Peter Kraft
    • Christopher A Haiman
    News & Views
    Nature Genetics
    Volume: 42, P: 819-820