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Showing 1–6 of 6 results
Advanced filters: Author: "Peter Libby" Clear advanced filters
  • An analysis of faecal samples reveals that obese people who take cholesterol-lowering statin drugs have a ‘healthier’ community of gut microorganisms than would be expected. What are the implications of this surprising finding?

    • Peter Libby
    News & Views
    Nature
    Volume: 581, P: 263-264
  • Recent advances in our understanding of the mechanisms of atherosclerosis, which is an inflammatory disease that involves the formation of plaques in the arteries, indicate that the immune response can both promote and reduce disease.

    • Göran K. Hansson
    • Peter Libby
    Reviews
    Nature Reviews Immunology
    Volume: 6, P: 508-519
  • Unstable plaques have been used as a target for imaging and drug discovery, and as a model of atherosclerosis in preclinical experiments. In this Review, Pasterkamp and colleagues describe the temporal shift in the characteristics of plaques in patients with acute coronary syndrome, and argue that the 'vulnerable plaque' concept might no longer be relevant to current practice.

    • Gerard Pasterkamp
    • Hester M. den Ruijter
    • Peter Libby
    Reviews
    Nature Reviews Cardiology
    Volume: 14, P: 21-29
  • In this timely Review, Drs Rocha and Libby discuss the commonalities in the pathophysiology of atherosclerosis and obesity, with a particular focus on inflammation—an important aspect of both diseases. The authors also examine the clinical implications of the mechanistic links between the two conditions.

    • Viviane Z. Rocha
    • Peter Libby
    Reviews
    Nature Reviews Cardiology
    Volume: 6, P: 399-409
  • Atherosclerosis is now widely considered to be a chronic inflammatory disease that is driven by the activities of many leukocyte subpopulations. Here, the authors describe the contribution of different immune-cell subsets to each stage of the disease, revealing complex and dynamic interactions.

    • Christian Weber
    • Alma Zernecke
    • Peter Libby
    Reviews
    Nature Reviews Immunology
    Volume: 8, P: 802-815