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Advanced filters: Author: "Peter S Linsley" Clear advanced filters

  • microRNA expression has been profiled in a broad range of cell types.

    • Lee P Lim
    • Peter S Linsley
    News & Views
    Nature Biotechnology
    Volume: 25, P: 996-997

  • The therapeutic potential of gene silencing by RNA interference has generated considerable interest and investment, with clinical trials now in progress in various disease areas. However, achieving target specificity remains a key challenge. Here, Jackson and Linsley discuss the off-target effects of small interfering RNAs and strategies aimed to mitigate them.

    • Aimee L. Jackson
    • Peter S. Linsley
    Reviews
    Nature Reviews Drug Discovery
    Volume: 9, P: 57-67